Generation and characterization of human induced pluripotent stem cells (iPSCs) from three patients with age-related macular degeneration carrying rare variants in the CFH gene

Generation and characterization of human induced pluripotent stem cells (iPSCs) from three patients with age-related macular degeneration carrying rare variants in the CFH gene

Blog Article

Age-related macular degeneration (AMD) is a major cause of vision loss among the elderly in the Western world.AMD is multifactorial eye disease with a strong genetic contribution.Here, we report the generation and characterization of induced pluripotent stem cells 3 Piece Outdoor Counter Height Dining Set (iPSCs) derived from peripheral blood mononuclear cells of three patients with AMD carrying Shower Heads rare variants in the complement factor H (CFH) gene.These cell lines were generated for cellular studies investigating the disease mechanisms and developing therapeutic interventions for AMD.